Hello
I need to do an LC/MSMS method for quantification on a compound that doesn't ionize into [M+H]+ (barely observed) but only into [M-H2O+H]+
Is there a problem with doing MS/MS on a [M-H2O+H]+ parent ion ?
(PS: negative ionization is not an…
Hi again Raina,
as I already told you this cannot be done with just one column, especially with the CO2 concentration up to 20% and water included and the necessity to analyze H2. This is an application we normally build an analyzer for. You need at…
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Operating like this puts sub-optimal flow into the GCMS ion source of more than 2 ml/min. Please make sure that you have a system with a turbomolecular high vacuum pump and not a diffusion pump as 2 ml/min exceeds the maximum allowable flow into a diffusion…
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Hi Margot,
It may well be that the column performance has deteriorated so much within the 7 months that the EasiVial standards are measured with poorer PDI values. The column performance can be tested with regular plate count determinations. It is a…
Hi sojeong,
every test report, delivered with aour columns, contains multiple specifications, but they are all measured with specialized systems and software. That means you might not be able to reproduce them identically. BTW for plate count you also…
Hi, I cannot configure the column compartment (CC) as it came integrated with the vial sampler on LC1290. We have the G7129B model for the integrated vial sampler and CC. I tried adding the column compartment details from the instrument configuration…
When the tuning is done at 3200 (+) everything is fine. When I change it to tune at 1700 (+) the masses are reasonably accurate. After it gets to the third mass (620) it appears that the entire spectrum shifts by about 1.5 AMU and the tuning fails. There…
Hi Siddhartha,
Thank you for contacting Cell Analysis Technical Support. Can you please go ahead and send us your System Files so that we can see what might be going on? These can be accessed in the Help Section of the Wave software. You can select…
This Information Applies To: Agilent MassHunter Qualitative Analysis Software
Issue
Error message prompted “Access to the path C:\Users\AgilentMad\AppData\Local\Temp\FILESPEC.TXT is denied" during search using NIST MS Program in MassHunter Qualitative...
This Information Applies To: Agilent AriaMx real-time PCR system
Issue
When sending a run configuration from the AriaMx PC software, no run configuration is transmitted. The expected blue confirmation icon does not appear at the bottom of the touch...
This Information Applies To: Agilent AriaMx real-time PCR system, AriaMx analysis software
Issue
Can the AriaMx software be used on Windows 11?
Resolution
The AriaMx a nalysis software 2.0 has not been validated for Windows 11, so Agilent...
This Information Applies To: Agilent AriaMx real-time PCR system
Issue
How to control more than one AriaMx with one PC.
Resolution
If you connect the PC and instruments using an ethernet cable, you will not be able to establish multiple connections...
This Information Applies To: Agilent AriaMx real-time PCR system, AriaMx analysis software
Issue
In the Export Data menu, after exporting data in a LIMS format, the output file's name is incomplete.
Background
An example of everything after...
This Information Applies To: Agilent AriaMx real-time PCR system, AriaMx analysis software
Issue
The AriaMx Data saving behavior when priming experiments from the PC is dependent upon whether the user is logged in or a Guest and whether the user...
This Information Applies To: Agilent OpenLab CDS
Issue
Sequence Creation Template allows users to create a sequence template that identifies the order of injections or actions in the sequence.
This article outlines the step-by-step instruction...
This Information Applies To: Agilent 6100 and 6400 Series LC/MS Systems
Issue
Tuning a mass spectrometer involves optimizing the voltages applied to various optical elements in the ion path to achieve the required mass accuracy, resolution, and...
This Information Applies To: Agilent OpenLab ChemStation
Issue
In OpenLab ChemStation, creating a result set by combining multiple existing result sets can be useful in the following scenarios:
Combining single samples, sequences, or a combination...
This Information Applies To: Agilent AriaMx real-time PCR system
Issue
The AriaMx analysis software shows an error when attempting to open a data file.
Background
The AriaMx analysis software can show several errors when something is wrong...