Hello camelia, I added tags to this post to increase visibility. One way to address this would be to set up a custom calculation to identify missing compounds for a given injection/signal. The below formula will output "No Calibrated Peak(s) Missing"…
The drops in baseline were still present when we blocked off the MS with a no-hole ferrule. Cleaning the source seemed to resolve the baseline issue and tune. Thinking it must have oxidized to some extent when the vacuum pump failed.
Hello, For the Servo Restart Failed error, it can be created from the pump drive not moving properly. It can also be cause by a blockage of the Inlet valve or Outlet valve. So you can try to loosen one of them and start the module and see if it gives…
Hey all, What is the primary difference between deuterium lamps 5182-1530 and 2140-0813? We recently replaced 5182-1530 with 2140-0813 on our 1100 HPLC but after the wavelength verification test, the lamp is failing the D2 alpha line deviation. Got 1…
My lab would like to have every run generate an Area Percent Report for every run with integrated peaks. All of my attempts have failed thus far. Can someone please give me the command line to enter in the DEUSER.MAC? Thanks!!
I spent the last couple days playing around with the ratios and I think I've succeeded! Thanks Ron! Here's what I ended up doing, for anyone else that might be trying the same thing. First, I will say these conditions only work with the 5 ppm DFTPP solution…
We have 6490A LCMS. Instrument works well but when I checked for autotune it failed. The data seems OK but now days I have to autotune every two weeks. Can anybody advise if I am over killing (by too many times autotuning) or it is a signal of instrument…
Dissolution testing is labor intensive as well as a technique and time dependent analytical procedure. A typical dissolution workflow consists of several steps including dissolution media preparation, media filling, introducing the dosage form into the…
The beginning of chromatography by the Russian botanist Tswett in 1903 was based on liquid phase chromatography (LC). Gas chromatography (GC) had its development in 1952. Supercritical fluid phase chromatography (SFC) began to be used in 1962.
The aim…
Hi, We have Standalone instrumnet connect to a PC running on OpenLAB Chemstation C.03 version, the PC runs on XP. We are now seeing issues like once the sequences are completed Automatic upload failed, can someone help us on this
This Information Applies To: Agilent GC Systems
Issue
This test isolates the point of contamination to the sample introduction system, which includes the gas supply, gas supply lines, and the sample inlet. It does not include the syringe or autosampler...
This Information Applies To: Agilent GC systems
Issue
Peak tailing is present in a chromatography peak when it has an excessive asymmetry with a trailing edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
T his Information Applies To: Agilent 8890/8860/7890/7820/6850/6890 GC Systems with TCD (Thermal Conductivity Detector)
Issue
Problems observed with thermal conductivity detector (TCD) results can have different underlying causes.
Resolution...
This Information Applies To: All GCs, 6890, 6850, 7890, 7820, 8890/8860, Intuvo 9000
Issue:
This article is a troubleshooting guide for when the Flame Ionization Detector (FID) does not ignite or the flame keeps going out.
Cause:
If the FID...
This Information Applies To: Agilent GC Systems with Flame Ionization Detector (FID)
Issue:
The Flame Ionization Detector (FID) jet could become clogged with ferrule material, column bleed, or heavy molecular analytes. The clogged jet will affect...
This Information Applies To: Agilent GC Systems with Split/Splitless (S/SL) inlet
Issue
Different liners are required for different high concentration, split analysis techniques including:
General use liners
Auto inject, general use
Auto...
This Information Applies To: Agilent GC Systems with Split/Splitless (S/SL) inlet
Issue
Different liners are required for different splitless trace analysis techniques including:
General use liners
Pressure, temperature, volume (PTV)
Hot...
This Information Applies To: Agilent 6890, 7890, 7820, 8890 and 8860 GC Systems with Split/Splitless (S/SL) inlet
Issue
Replacement of the Gold Seal is required as part of inlet maintenance. Replacement is required when the performance of the inlet...
This Information Applies To: Agilent GC Systems with Micro-ECD.
Issue
The Wipe Test is an annual test that performed by end user of the micro-ECD (Micro Electron Capture Detector or uECD) to help ensure radioactive safety when using the detector...
This Information Applies To: Agilent GC Systems with thermal conductivity detector (TCD)
Issue
Baking the thermal conductivity detector (TCD) at high temperatures can remove sample contaminants that have deposited on the detector surfaces.
Items...