By: karen.krauel-goellner
It was with great pleasure and excitement to host the first Agilent 400-DS workshop at our customer center in Waldbronn, Germany on January 17, 2023. This hybrid event included attendees and presenters joining us ...
The Agilent NanoDis system combines traditional USP Apparatus 1 and 2 instrumentation with automation and compliance in an ideal system for scientists looking to optimize formulation development. While initially designed for the dissolution...
The Dissolution Discussion Group (DDG) is an independent forum which gives you the opportunity to ask questions and discuss key topics that affect the day-to-day task of developing, performing, and validating dissolution methods and their relat...
Deaeration, or degassing, is the controlled process of removing excess dissolved gases, primarily air, from dissolution media. When performing dissolution testing, this can be one of the biggest headaches in the lab; and, if not done properly, is one...
Filter selection is one of the most critical and misunderstood aspects of Dissolution. This post includes key points regarding this topic as well as important links to further information from Agilent and Cytiva filtration experts.
Working with a new formulation typically requires development of a new dissolution method. What apparatus or media should you use? If the product is already well established, do you need to start from scratch? In this post, Ken Boda delivers key advice as well as a collection of resources available to help get you moving in the right direction.
Low-dose formulations and medical devices are becoming more common. For these products, typical dissolution volumes of 500 - 900 mL are too high to get appropriate analysis on UV-Vis or HPLC and smaller volumes are needed. In this post, Agilent&rsquo...
(The following article is paraphrased from a previous LinkedIn post by kenboda, Agilent’s US Product Specialist for Dissolution.)
The vast majority of dissolutions are performed using USP Apparatus 1 (baskets) and 2 (paddles), but when sho...
The Apex (Peak) vessel continues to gain momentum in the dissolution testing arena. A recently published Stimuli article from industry experts (link at bottom of article) reflects this position with supporting data from several case studies. Hear Agi...
Sink condition is mentioned a lot when it comes to dissolution testing, but its importance is often left out. The background and relevance of this topic is further described and discussed by kenboda , Dissolution Product Specialist at Agilent. T...
(originally posted by Ken Boda, Dissolution Product Specialist on LinkedIn)
One question I frequently get is about Q in the USP. What is Q? How to I determine Q? How do I interpret the acceptance tables?
USP defines Q as the quantity or the "amount o...
