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We've been having issues with our LC-MS/MS 1260/6490 and 1290/6470 systems giving "LC Offline" errors when the instrument is all ready to go and we start a worklist. It clearly is connected, because it's showing the LC status the entire time. We're using…
From a GCMS perspective, 1.9 ml/min into the ion source is not optimal. The MS prefers down around 1.2 ml/min. Sensitivity is better and spectral tilt is more typical.
Septum head or septumless head? What is your gas supply pressure? When was the last…
Hello,
Question 1: Are you opening a snapshot or using review completed injections to open the in-progress injections? Is it possible you were on a replicate injection when trying to change the type.
Question 2: Andy is correct you must have the…
Helllo mighty Marty,
we have only one Infinity II device, so it can be useful. It works same as your example. But if we are going to compare this system with GC catalog it seems to be very painful to write all the info again and again when you are going…
Hello payninater ,
To utilize the inherited calibration curve you will need to copy the cal levels to the other targets. If you are doing this make certain your unknown targets have the same ISTD assigned. Quant does not verify this and simply applies…
Hello payninater ,
It is not possible to enter responses manually in the Method Editor.
As far as I know there should be no issue with setting your sample type and level in the batch table, creating a new method from acquired data, creating levels…
Hello HowngChan ,
For a dual needle multisampler the purge timer does not start until after the method with a different gradient or solvent system is loaded. By default, the worklist will have a 10 minute Wait Time for Ready. This can be set to a maximum…
This Information Applies To: HES ion source in 5977B/C GC/MSD, 7010 triple quadrupole GC/MS systems
Issue
The filaments are replaced as part of routine maintenance, or when they break (zero output current).
Items Required
Gloves, nylon,...
This Information Applies To: Agilent 5977A/B/C GC/MSD
Issue
The Electron Multiplier Horn must be replaced when it is contaminated or the EMV value reaches 3000 V with a clean ion source.
Items Required
Electron multiplier horn (5977B/C:...
This Information Applies To: Agilent 5973/ 5975/5977 GC/MSD with rotary vane foreline pump
Issue:
The oil mist filter is recommended to be replaced annually. If the color of the filter has changed or there is smell from the filter, the oil mist...
This Information Applies To: Agilent EI Source
Issue:
During normal operation of the GC/MS, the EI SST/Inert ion source will need to be disassembled to proceed with abrasive ion source cleaning and / or routine replacement of consumable parts (filaments...
This Information Applies To: Agilent G7129A/B/C Vialsampler
Issue:
Replacing the needle and needle seat of the Vialsampler is required when:
The needle is visibly damaged.
Leaks or blockages in the vialsampler are observed, especially between...
This Information Applies To: Agilent G1311A/B/C, G7111A/B, Quaternary Pumps, and G1310A/B, G7110B Isocratic Pumps, G1312A/B/C, G7112B Binary Pumps
Issue:
How to diagnose no flow or no pressure issues on binary, quaternary, or isocratic pumps.
...
This Information Applies To: Agilent UV and RID detectors
Issue
A clogged flow cell causes high backpressure. The clog can be removed by flushing the system with solvents at high pressure. If you suspect a clog or experience high backpressure due...
This Information Applies To: Agilent G1312X and G7112X binary pumps.
Issue:
A blockage before the pressure sensor, e.g. in a pump head, will not give a high pressure or overpressure system error. Instead, the pump may show one of various error messages...
This Information Applies To: Agilent 1100, 1200, 1260 LC Pumps.
Issue:
The following procedure allows the cleaning of residue from the pump's check valves, often caused by polymerization of aged acetonitrile or salt-based solutions that may prevent...
This Information Applies To: Agilent LC Systems
Issue
After analyzing dirty or concentrated samples, some sample compounds may retain in the column and other parts of the HPLC system. If the column re-equilibration after each run is not enough to...