ICP MassHunter installation error


I am trying to install the G7201D version of ICP MassHunter on a 1909 Windows 10 laptop.

It goes through the initial process and then errors with a code of 0xe0434352.

Some additional research implies this is a .Net error but a repair install of the .Net has made no difference.

This is a snippet of the log file showing the step its failing at

[3A0C:2884][2021-06-24T11:11:12]i301: Applying execute package: PreAction, action: Install, path: C:\ProgramData\Package Cache\{6d6e7f26-60a8-4901-a523-9875ec509b0f}v4.1.1.38\BundleCustomAction.exe, arguments: '"C:\ProgramData\Package Cache\{6d6e7f26-60a8-4901-a523-9875ec509b0f}v4.1.1.38\BundleCustomAction.exe" /PREACTION "/USERDIR=" /OPASX520=0 /OPSPS4=0 /OPIAS=0 /OPBOOTP=0 /OPSVT=0 /OPGCSETTINGS=0 /OPSKIPMS=0 "/L=C:\Users\seatoa\AppData\Local\Temp\ICP-MS_MassHunter_Workstation_Bundle_20210624111101_000_PreAction.log"'
[3A0C:2884][2021-06-24T11:11:19]e000: Error 0xe0434352: Process returned error: 0xe0434352
[3A0C:2884][2021-06-24T11:11:19]e000: Error 0xe0434352: Failed to execute EXE package.
[2DD4:1F04][2021-06-24T11:11:19]e000: Error 0xe0434352: Failed to configure per-machine EXE package.
[2DD4:1F04][2021-06-24T11:11:19]i319: Applied execute package: PreAction, result: 0xe0434352, restart: None
[2DD4:1F04][2021-06-24T11:11:19]e000: Error 0xe0434352: Failed to execute EXE package.
[3A0C:2884][2021-06-24T11:11:19]i351: Removing cached package: PreAction, from path: C:\ProgramData\Package Cache\{6d6e7f26-60a8-4901-a523-9875ec509b0f}v4.1.1.38\

Any suggestions gratefully received


  • Hi

    Are you installing software in new PC or in old PC by uninstalling masshunter then again installing?

  • Hi

    This is a new install of MassHunter.   It did have the help tools installed which I have removed.

  • Hi Bob,

    MassHunter installation may be a challenge, if you are trying to install it on a non-agilent PC. This is due to several settings on Windows level. Did you follow the full steps for installing the MassHunter on a non-agilent system? Windows display language must be English and regional formatting is also very important. If you applied everything as suggested in the installation guide and your installation still fails, please contact your local Agilent customercare team, so that an engineer can offer you a remote troubleshooting. 



  • included with the installation media, is a Microsoft folder. In this folder are some .Net Framework updates, Visual C++ Runtime library updates and Visual Studio updates. Run all of these. Your OS may not need these, but it will tell you. If your OS recognizes that they are already installed, opt for a repair. For the after going through all Visual C++ Runtime Libraries, there will be a 32-bit and 64-bit installer; run both. When done reboot.

    Configure .NET Framework by going to 'Turn Windows Functions On or Off' You can search for this in the Windows Search tool. When the applet opens, look at first two options. This will be the .NET Framework  configuration. Expand these and deactivate all and click OK. After Windows Update reconfigures, return and activate all under .NET Framework 3.5 (the first of the two main features in the applet). Doing this will activate ASP .NET 4.X under .NET Framework 4.7/8; this is OK.

    Reboot and try the MassHunter installer again. Use repair option, if it asks.

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