We've been having issues with our LC-MS/MS 1260/6490 and 1290/6470 systems giving "LC Offline" errors when the instrument is all ready to go and we start a worklist. It clearly is connected, because it's showing the LC status the entire time. We're using…
From a GCMS perspective, 1.9 ml/min into the ion source is not optimal. The MS prefers down around 1.2 ml/min. Sensitivity is better and spectral tilt is more typical.
Septum head or septumless head? What is your gas supply pressure? When was the last…
Hello,
Question 1: Are you opening a snapshot or using review completed injections to open the in-progress injections? Is it possible you were on a replicate injection when trying to change the type.
Question 2: Andy is correct you must have the…
Helllo mighty Marty,
we have only one Infinity II device, so it can be useful. It works same as your example. But if we are going to compare this system with GC catalog it seems to be very painful to write all the info again and again when you are going…
Hello payninater ,
To utilize the inherited calibration curve you will need to copy the cal levels to the other targets. If you are doing this make certain your unknown targets have the same ISTD assigned. Quant does not verify this and simply applies…
Hello payninater ,
It is not possible to enter responses manually in the Method Editor.
As far as I know there should be no issue with setting your sample type and level in the batch table, creating a new method from acquired data, creating levels…
Hello HowngChan ,
For a dual needle multisampler the purge timer does not start until after the method with a different gradient or solvent system is loaded. By default, the worklist will have a 10 minute Wait Time for Ready. This can be set to a maximum…
This Information Applies To: Agilent Liquid Chromatography (LC) systems
Issue:
Shutting down the HPLC for a long period requires following this general procedure to prevent damage to the system and the column.
Steps to follow:
Store the...
This Information Applies To: Agilent G7129A/B Autosampler with Sample Thermostat/Cooler G7167-60101 or G7167-60005.
Issue:
The autosampler may stop working from time to time, potentially giving off loud noises and switching off the light. The only...
This Information Applies To: Agilent 5977A/B GC/MSD with EI source, EI Extractor Source, or CI Source.
Issue:
During normal operation of the GC/MSD, the source will require cleaning. It is time to clean the source when:
There is a loss in analyte...
This Information Applies To: Agilent HES source, Agilent 5977 Series GC/MSD
Issue:
During normal operation of the GC/MSD, the source will require cleaning. It is time to clean the source when:
There is a loss in analyte response not improving...
This Information Applies To: Agilent 5977 and 5975 Series GC/MSD systems
Issue
The autotune fails and reports the error Tune action stopped: Gain and offset = 0 and peaks are too narrow!
Resolution
The MSD autotune program is run after routine...
This Information Applies To: Agilent ICP-MS systems (7700/7800/7850/7900/8800/8900)
Issue
Condition new or cleaned ICP-MS skimmer cones and sampler cones by aspirating a Conditioning Solution before use.
Background
Drift up can be a sign of...
Turn On the GC/MS Interface and Oven Using OpenLab CDS
Multiple Results
This Information Applies To: Agilent GC/MS instruments controlled by OpenLab CDS software
Issue
Turning on the GC/MS interface heater and Oven using OpenLab CDS software.
Steps to Follow
From the Home tab, click Method > Instrument Setup...
This Information Applies To: Agilent ICP-MS systems (7700/7800/7850/7900)
Issue
The signal monitor function in MassHunter can help with troubleshooting low sensitivity, carry over, contamination, or high background. It can also be used to optimize...
This Information Applies To: Agilent UV detectors (Variable Wavelength Detectors, Multiple Wavelength Detectors, and Diode Array Detectors)
Issue
Checking accumulated hours on the UV lamp.
Steps to Follow
There are four ways to check the accumulated...
This Information Applies To: Agilent 7700/7800/7850/7900/8800/8900 ICP-MS
Issue:
Poor internal standard (ISTD) mixing can cause high relative standard deviation (RSD).
The recommendations in this article are applicable if:
It takes a long...