ICP-MS Cone Conditioning

Answer

This Information Applies To: Agilent ICP-MS systems (7700/7800/7850/7900/8800/8900)

Issue

Condition new or cleaned ICP-MS skimmer cones and sampler cones by aspirating a Conditioning Solution before use.

Background

Drift up can be a sign of poor cone conditioning. During analysis as the cones become more conditioned through use, they become more inert; and interfere less with analytes, causing the signal to increase over time.

If signal drift during a batch is observed after cleaning or replacing the cones, confirm that the cones have been conditioned sufficiently.

• Brand-new cones will have a shiny surface before conditioning (Figure 1; Item 1).
• Conditioned cones will have a patina-like coating will form on the surface (Figure 1; Item 2).

Figure 1. Skimmer Cones
1. New unconditioned skimmer cone 2. Conditioned skimmer cone

Items Required

• Conditioning Solution such as:
  • 50 ppm Calcium in 1% HNO3
  • 0.2% NaCl in 1% HNO3
  • ICS-A solution (used for environmental applications)
• 1% HNO3 Rinse

Steps to Follow

1. Install the new (or cleaned cones).
2. Light the plasma.
3. Introduce the Conditioning Solution (see Items Required section) for 30–60 minutes.
4. Introduce the 1% HNO3 rinse solution for 60 minutes.

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