The drops in baseline were still present when we blocked off the MS with a no-hole ferrule. Cleaning the source seemed to resolve the baseline issue and tune. Thinking it must have oxidized to some extent when the vacuum pump failed.
Hello, For the Servo Restart Failed error, it can be created from the pump drive not moving properly. It can also be cause by a blockage of the Inlet valve or Outlet valve. So you can try to loosen one of them and start the module and see if it gives…
Hey all, What is the primary difference between deuterium lamps 5182-1530 and 2140-0813? We recently replaced 5182-1530 with 2140-0813 on our 1100 HPLC but after the wavelength verification test, the lamp is failing the D2 alpha line deviation. Got 1…
My lab would like to have every run generate an Area Percent Report for every run with integrated peaks. All of my attempts have failed thus far. Can someone please give me the command line to enter in the DEUSER.MAC? Thanks!!
I spent the last couple days playing around with the ratios and I think I've succeeded! Thanks Ron! Here's what I ended up doing, for anyone else that might be trying the same thing. First, I will say these conditions only work with the 5 ppm DFTPP solution…
We have 6490A LCMS. Instrument works well but when I checked for autotune it failed. The data seems OK but now days I have to autotune every two weeks. Can anybody advise if I am over killing (by too many times autotuning) or it is a signal of instrument…
Dissolution testing is labor intensive as well as a technique and time dependent analytical procedure. A typical dissolution workflow consists of several steps including dissolution media preparation, media filling, introducing the dosage form into the…
The beginning of chromatography by the Russian botanist Tswett in 1903 was based on liquid phase chromatography (LC). Gas chromatography (GC) had its development in 1952. Supercritical fluid phase chromatography (SFC) began to be used in 1962.
The aim…
Hi, We have Standalone instrumnet connect to a PC running on OpenLAB Chemstation C.03 version, the PC runs on XP. We are now seeing issues like once the sequences are completed Automatic upload failed, can someone help us on this
Hi mr.white, I already did several upgrades from OpenLAB EZChrom to OpenLAB 2.x. let me write some pros/cons: Pros - fully virtualized, support server 2019 and Windows 10 - easy upgrade (same integrator, raw data can be copied and opened, method imported…
This Information Applies To: All Agilent Gas Chromatographs, 6890, 6850, 7890, 7820, 8890, and 8860.
Issue:
A quick reference guide on the capillary column installation for the GC.
Inlets
Detectors
Split/splitless inlet Purged...
How to Add a GC Instrument in Agilent OpenLab CDS (Ver 2.x)
Multiple Results
This Information Applies To: Agilent OpenLab CDS (Ver 2.x)
Content:
The following procedure shows how to add a GC instrument in OpenLab CDS (Ver 2.x).
Steps to Follow:
1. Open OpenLab CDS Control Panel, in the Instruments interface, select...
This Information Applies To: Agilent Intuvo 9000, 8860, 8890, 7890A/B, 7820A, 6890, 6850 GC Systems with Split/Splitless, or Multimode Inlets.
Issue:
This article describes how to replace the inlet septum for Split/Splitless and multimode inlets...
This Information Applies To: Agilent GC Systems
Issue
The data rate determines the number of sampling points across the chromatographic peak and the sample background. The data rate is based on the width of the analyte speak (in minutes) and the...
This Information Applies To: Agilent GC Systems
Issue
Excessive baseline noise can be introduced at different points including sample preparation, sample introduction, separation, and the detector. The excessive background can cause reduced signal...
This Information Applies To: Agilent GC Systems
Issue
Baseline instability that is not reproducible across multiple runs can be introduced at different points including sample introduction, separation, and the detector. The baseline instability...
This Information Applies To: Agilent GC Systems
Issue
Peak fronting is present in a chromatography peak when it has an excessive asymmetry with a leading edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
This Information Applies To: Agilent GC Systems
Issue
A shift in retention time can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
A change in peak size can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
Peak splitting is when a single compound is shown in the chromatogram as two peaks usually unresolved, or one of the peaks is a shoulder.
Other chromatographic problems are identified in Basic...