megaflorch - this was fairly old topic and I wasn't sure if you completed your standards/sample prep. I use a similar technique to get my analytes within a better working linear range with respect to my GC-FID. Your logic is good.... here is my standard…
I am having trouble separating methyl methacrylate (MMA) from another peak. The interfering compound, appearing in the front, is identified by library as 3,3-dimethyl-2-butanone and it is inherent to the sample. MMA appears as the split/tailing peak.…
I have recently ran two standards on the Cary 630 FT-IR using the ATR module - qualitative search. One is Heptanes and the other is N-Heptane.
I then ran four samples - three were N-Heptane, the other was Heptanes and compared them to the two standards…
I went through everything I could find, but it appears that BootP doesn't work properly in Windows 10 and even when you follow the instructions it fails. As I mentioned above, the only way I found to get it working was to replace the JetDirect card with…
I have Chemstation C.01.08 [210]. Whenever I try to run a partial sequence, I get the 'Initialization of Sequence Failed' error message. From what I could find online, that issue was supposed to be solved in C.01.08 version of the software. I have Unique…
Hi,
I am currently running a USP <467> protocol which monitors the recovery of: methanol, ethanol, acetone, isopropyl alcohol, hexanes, and toluene. I make a standard solution using DMAC with known amounts of solvent and use the same solution to spike…
You can definitely set up an intelligent report to do what you want, but there is a much easier way to do this in OpenLAB ChemStation. When you create a calibration table, ChemStation gives you an option to 'Calculate Signals Separately': When selected…
I did a lens ramp on the failed BFB_AT and the emission ramp for 50 amu was very choppy. Setting the emission at 50 amu is where the tune process fails. Could this be due to a hardware problem?
Hi Lakshmi, Here is the reply from our compliance group.... Traceability and Audit Trails Data are generated by the same native chromatography data system (CDS) used in the daily operation of the instrument, which controls the system being qualified during…
Hi,
Every time we vent and vacuum down the MS2 auto tune fails with the high mass.
I've tried to tune from factory settings and manual tune using a file that was used prior to the shutdown.
The instrument is second hand so we have had the vendor…
This Information Applies To: Agilent GC Systems
Issue
Excessive baseline noise can be introduced at different points including sample preparation, sample introduction, separation, and the detector. The excessive background can cause reduced signal...
This Information Applies To: Agilent GC Systems
Issue
Baseline instability that is not reproducible across multiple runs can be introduced at different points including sample introduction, separation, and the detector. The baseline instability...
This Information Applies To: Agilent GC Systems
Issue
Peak fronting is present in a chromatography peak when it has an excessive asymmetry with a leading edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
This Information Applies To: Agilent GC Systems
Issue
A shift in retention time can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
A change in peak size can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
Peak splitting is when a single compound is shown in the chromatogram as two peaks usually unresolved, or one of the peaks is a shoulder.
Other chromatographic problems are identified in Basic...
This Information Applies To: Agilent GC Systems
Issue
This test isolates the point of contamination to the sample introduction system, which includes the gas supply, gas supply lines, and the sample inlet. It does not include the syringe or autosampler...
This Information Applies To: Agilent GC systems
Issue
Peak tailing is present in a chromatography peak when it has an excessive asymmetry with a trailing edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
T his Information Applies To: Agilent 8890/8860/7890/7820/6850/6890 GC Systems with TCD (Thermal Conductivity Detector)
Issue
Problems observed with thermal conductivity detector (TCD) results can have different underlying causes.
Resolution...
This Information Applies To: All GCs, 6890, 6850, 7890, 7820, 8890/8860, Intuvo 9000
Issue:
This article is a troubleshooting guide for when the Flame Ionization Detector (FID) does not ignite or the flame keeps going out.
Cause:
If the FID...