Learn about how to check and extend the lifetime of peristaltic pump tubing; prevent and remove nebulizer blockages; clean the nebulizer and improve precision and reduce memory effects with spray chamber cleaning.
Preventative maintenance is crucial…
Learn more about accurate ICP-MS standard preparation, sample introduction, diagnosis of sample introduction issues, and preventive ICP-MS maintenance guidelines. In this video we provide simple steps to improve sensitivity and accuracy, precision, and…
If you have data associated with a worksheet you cannot make modifications to it. Depending on your software version, you will need to either do "Save As" and give it another name, or create a new worksheet from template. Then the new worksheet will not…
Hello. You have to adjust Nitrogen pressure to get the blue bar inside green area. Pressure regulator is located on the right side of the 4107. It should be ~ 600kPa.
Hello mipastor,
Thank you for your response. I think we do have problem with the MS2 heater. Agilent customer support hinted that it might be sensor problem or the board so service engineer will have to take a look.
The Digest of upcoming webinars has been updated as of April 23.
The new Agilent Community Group, GPC/SEC Solutions Group is hosting a webinar series in partnership with Dow in April: A Journey through SEC, Light Scattering, and 2D-LC for Macromolecules…
In the previous post, I talked about the merits of automated sampling in the dissolution workflow . Here, I will provide some information about how to validate your automated dissolution system, using the 850-DS Sampling station from Agilent as an example…
You might be able to use HPLC-SEC on those with an Aquagel-like column. Check these literature links for help:
https://doi.org/10.1016/0021-9673(71)80010-9
https://doi.org/10.1208/s12248-017-0126-0
You do this with a Restek column! You cannot get a better resolution by changing just parameters with this cphase. You need a different selectivity to have a chance, maybe use a DB-WAX UltraInert.
For glucose a 87H type is ok as it uses Ion Exclusion Chromatography for the separation, the phases contain benzenesulfonic acid group (and will interact with anions in ion exchange mode). Phosphoric acid does not interact with sulfonic acid groups as…
This Information Applies To: Agilent GC Systems
Issue
Excessive baseline noise can be introduced at different points including sample preparation, sample introduction, separation, and the detector. The excessive background can cause reduced signal...
This Information Applies To: Agilent GC Systems
Issue
Baseline instability that is not reproducible across multiple runs can be introduced at different points including sample introduction, separation, and the detector. The baseline instability...
This Information Applies To: Agilent GC Systems
Issue
Peak fronting is present in a chromatography peak when it has an excessive asymmetry with a leading edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
This Information Applies To: Agilent GC Systems
Issue
A shift in retention time can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
A change in peak size can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
Peak splitting is when a single compound is shown in the chromatogram as two peaks usually unresolved, or one of the peaks is a shoulder.
Other chromatographic problems are identified in Basic...
This Information Applies To: Agilent GC Systems
Issue
This test isolates the point of contamination to the sample introduction system, which includes the gas supply, gas supply lines, and the sample inlet. It does not include the syringe or autosampler...
This Information Applies To: Agilent GC systems
Issue
Peak tailing is present in a chromatography peak when it has an excessive asymmetry with a trailing edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
T his Information Applies To: Agilent 8890/8860/7890/7820/6850/6890 GC Systems with TCD (Thermal Conductivity Detector)
Issue
Problems observed with thermal conductivity detector (TCD) results can have different underlying causes.
Resolution...
This Information Applies To: All GCs, 6890, 6850, 7890, 7820, 8890/8860, Intuvo 9000
Issue:
This article is a troubleshooting guide for when the Flame Ionization Detector (FID) does not ignite or the flame keeps going out.
Cause:
If the FID...