In the previous post, I talked about the merits of automated sampling in the dissolution workflow . Here, I will provide some information about how to validate your automated dissolution system, using the 850-DS Sampling station from Agilent as an example…
You might be able to use HPLC-SEC on those with an Aquagel-like column. Check these literature links for help:
https://doi.org/10.1016/0021-9673(71)80010-9
https://doi.org/10.1208/s12248-017-0126-0
You do this with a Restek column! You cannot get a better resolution by changing just parameters with this cphase. You need a different selectivity to have a chance, maybe use a DB-WAX UltraInert.
For glucose a 87H type is ok as it uses Ion Exclusion Chromatography for the separation, the phases contain benzenesulfonic acid group (and will interact with anions in ion exchange mode). Phosphoric acid does not interact with sulfonic acid groups as…
thanks for sharing the information. It saved my day. But to delete the mentioned file I had to call helpdesk to grant me permission. No way to delete with my regular credentials.
Agilent offers these two services for the IDP-7 Dry Scroll Pump: 1. The Agilent Rapid Exchange Service replaces your pump with a refurbished one • You can send your unit back (exchange) once the replacement unit arrives • Warranty period is 1 year from…
hello,
How to use the Add-ins Blank substraction in Mass Hunter V10.1 without a calibration curve? It seems like it is not possible without a calibration curve but I'm doing semi-quantitative work so I don't have a calibration curve.
Will that feature…
This Information Applies To: 5200/5300/5400 Fragment Analyzer, Fragment Analyzer controller software
Issue:
Over time the dynamic coating polymer on the capillaries needs to be refreshed. Failure to do so can lead to a loss of performance. Indicators...
This Information Applies To: Agilent ICP-MS (7700/7800/7850/7900/8800/8900)
Issue
Elevated doubly charged values that are greater than 3% for x-lens configuration or greater than 7% for s-lens configuration, can be caused by contamination, or an...
This Information Applies To: Agilent 6200 Series TOF and 6500 Series Q-TOF Systems
Issue
Instructions on how to correctly dilute the tune mix for 6200 Series TOF and 6500 Series Q-TOF systems depending on source type.
Background
If the Tune...
This Information Applies To: Agilent MassHunter Qualitative Analysis Software version 10.0
Issue
The Agilent MassHunter Qualitative software can generate qualitative analysis reports, which may include sample chromatogram information and sample...
This Information Applies To: Agilent MassHunter Qualitative Analysis Software version 10.0 or higher
Issue
Identifying compounds using a spectral library is essential in qualitative analysis. This article will describe how to load a data file and...
This Information Applies To: Agilent ICP-MS Systems
Issue
The Helium cell gas line on the ICP-MS may be contaminated with air and moisture in case of a tank replacement, or if the instrument was not used for an extended amount of time. Purging the...
This Information Applies To: Agilent MassHunter Quantitative Analysis Software
Issue
The Calibration Curve window tools help with setting an appropriate calibration curve for each compound in the calibration table.
The Calibration Curve window...
This Information Applies To: Agilent MassHunter Quantitative Analysis "Quant-My-Way" user interface (version B.09.00 or later)
Issue
To process the data files in the batch and obtain quantitative results, you must either create a new quantitative...
This Information Applies To: Agilent MassHunter Qualitative and Quantitative Analysis
Issue
Calculation of signal-to-noise in MassHunter is done using the same routine for both Qualitative and Quantitative Analysis. However, there are differences...
This Information Applies To: Agilent GC/MS MassHunter Data Acquisition Software
Issue
Multiple samples can be run without user intervention using an Automated Liquid Sampler (ALS) in combination with a Sequence.
Users can perform simple edits...