Binary code error and won't open MassHunter Quant Analysis

Question

For some reason a group of us can not open the Mass Hunter Quantitative analysis software. We keep an error code that says "Failed to open batch file. Failed to read binary batch file. We can't analyze any of our bin files.

howard_sanford · Answer

Hi kharrison77 , Another thing you can do is to check with your IT department and see if they have enabled the Federal Information Processing Standard (FIPS) enforcement policy in Windows. This is commonly done on US government computer systems. Currently no versions of quant are compatible with this policy. The error you are receiving is what you will see if FIPS is enabled and you try to open or save a batch. Compatibility is being investigated for future releases but there is currently no ETA on when this will be available. Currently the only solution is to request exemption for your PC from the policy.

howard_sanford · Answer

Hello Columbia_METALab , 
 I don't believe this was a known issue with Quant B.05, though it is out of support at this point. I can suggest a few things to try. 
 First would be general PC maintenance. Clean up Windows temp files and defragment the hard drive. 
 Next you can try to reset quant's user preferences. In current versions there is a tool for this called Restore User Settings. You can check in the Windows Start menu under Agilent MassHunter Quantitative->Quantitative Analysis Tools->Restore User Settings 
 Before doing this make certain you have any custom column or screen layouts saved in Quant. Also make note of what report method you are using, as this information will also be cleared when you use the tool. Then close all open copies of Quant and run the tool. 
 If that tool is not available, you can manually clear the preferences by going to the currently logged in user&rsquo;s appdata folders. The easiest way to locate these is to enter %appdata% into the location line in the file browser. This should go to C:\User\logged in username\AppData\Roaming. From there go to the Agilent_Technologies,_Inc folder and delete the MassHunter Quant folder. 
 Another possibility may be a corrupted quant method. You could try making a new method from acquired data, or loading a method from a batch that was created before you began having these issues.

Binary code error and won't open MassHunter Quant Analysis

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