MS instruments must maintain a flow of drying Gas and, Nebulizer, AJS

Hi, Anyone please help me to explain Why must maintain the flow of drying Gas and, Nebulizer, AJS when the instrument in standby?

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  • The source of your instrument is connected to the waste bottle via the plastic corrugated tube. The Mass spec is under vacuum and is always drawing from the source, Usually this is nitrogen and it is exiting the source with a very small positive pressure. If the nitrogen supply is lost, the MS still pulls vacuum and must take something from somewhere and can then back stream from the waste container and contaminate the system. Worst case if the exhaust from your rough pump and waste bottle are not separate, as recommended in the site prep checklist, oil mist from the pump exhaust can be back streamed into the source and then further into the instrument.

  • Yep! But I'm comparing to MS system of Waters corp., to seen that Agilent need to improve this. Their system usually will turn off Nitrogen gas when the system in Standby status. This is really a benefit, because will help to check MS system issues separately with Generation Nitrogen gas when no have nitrogen flow gas. 

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