MS instruments must maintain a flow of drying Gas and, Nebulizer, AJS

To ensure that the spray chamber continues to only contain nitrogen; specifically keeping oxygen out of the spray chamber/capillary/vacuum system.

/Andy

To ensure that the spray chamber continues to only contain nitrogen; specifically keeping oxygen out of the spray chamber/capillary/vacuum system.

/Andy

Thanks Andy.

Could you tell clearly the effect of keeping oxygen out of Spray chamber/Capillary/Vacuum system? Because if it affected to system, when I vented system for long time in not use, maybe in contradiction with that. And as I know, with MS Waters system, it doesn't need to keep the nitrogen flow when the system is in standby status.

If you vented the system, then there is no need for nitrogen supply since the capillary and quadrupole temperatures are not kept high.  The system is vented using nitrogen from the gas supply, so the inside of the vacuum chamber is kept free of oxygen and moisture.  If left vented for a long period of time, any oxygen and moisture will be pumped away as the system is brought back under vacuum.