Triethylamine Contamination

Hi dong0002,

Were you doing negative ion before? TEA is a very difficult contamination to remove.

You can also try the following:

1. Rinse the source with isopropanol, water, 25% nitric acid (15'), water (1,5 h),(remove from MS)

2. Clean the whole ion path , depends on MS 


You will also need to clean the whole LC.

3. Exchanging all peek-capillaries
4. ultrasonic of the rotor seals in isopropanol
5. Rinse the whole hplc with 25% nitric acid for 15 Minutes
6. Rinse the whole system with water, purge the pulse damper several times
7. Rinse the system one night with 50% isopropanol/water with 0.1% FA

You can also try the following:

1. Rinse the source with isopropanol, water, 25% nitric acid (15'), water (1,5 h),(remove from MS)

2. Clean the whole ion path , depends on MS 


You will also need to clean the whole LC.

3. Exchanging all peek-capillaries
4. ultrasonic of the rotor seals in isopropanol
5. Rinse the whole hplc with 25% nitric acid for 15 Minutes
6. Rinse the whole system with water, purge the pulse damper several times
7. Rinse the system one night with 50% isopropanol/water with 0.1% FA

Thank you for your answer