If the HiVac pump is off - the system is not under vacuum to be able to run. The MS source and quad cannot be heated until the system is under vacuum.
The directions on how to vent and pump down the MS are in the Operating manual and also the Troubleshooting…
The graphite must deform to seal. It can only deform one time as there is no spring-back. Install it with the inlet cold and the inlet pressure set to zero psi. I like to put the liner in, then place the seal around it using a gloved hand, then tighten…
I have been working with Thermo Orbitrap Exploris 480.
Which type of Agilent Q-TOF MS could have similar performance compared to the Thermo LC-MS instrument?
Since i retired from the previous company for private reason, I am trying to find another…
Thanks Chris. as you are expected, the "Round Thing" was main cause for this issue. i clean both the sensor and Vaccum Fan. Since it was more than 10 year front panel never been inspected. now it running again normally. Againn.. Thanks for your advice…
Hello srlee ,
This would not be a tested or supported workflow. While GCMS SQ data can be processed, in limited testing it appears that if Profinder see ESI data it assumes it is accurate mass. Even attempting to open up the mass filters to something…
Hi! We have been experiencing issues with the sensitivity of our SpectrAA-50/55 using a nitrous oxide/acetylene flame to quantify vanadium. We have been using this setup fairly consistently to quantify vanadium in solution for ~2 years now and have not…
Hello,
So first of all, if the entries you need are numeric and per compound, I would use a CC constants file. There are ways to create one big constants file for all your compounds and use keys values to pull specific columns by method or other values…
This Information Applies To: Agilent GC Systems
Issue
A shift in retention time can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
A change in peak size can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
Peak splitting is when a single compound is shown in the chromatogram as two peaks usually unresolved, or one of the peaks is a shoulder.
Other chromatographic problems are identified in Basic...
This Information Applies To: Agilent GC Systems
Issue
This test isolates the point of contamination to the sample introduction system, which includes the gas supply, gas supply lines, and the sample inlet. It does not include the syringe or autosampler...
This Information Applies To: Agilent GC systems
Issue
Peak tailing is present in a chromatography peak when it has an excessive asymmetry with a trailing edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
T his Information Applies To: Agilent 8890/8860/7890/7820/6850/6890 GC Systems with TCD (Thermal Conductivity Detector)
Issue
Problems observed with thermal conductivity detector (TCD) results can have different underlying causes.
Resolution...
This Information Applies To: All GCs, 6890, 6850, 7890, 7820, 8890/8860, Intuvo 9000
Issue:
This article is a troubleshooting guide for when the Flame Ionization Detector (FID) does not ignite or the flame keeps going out.
Cause:
If the FID...
This Information Applies To: Agilent GC Systems with Flame Ionization Detector (FID)
Issue:
The Flame Ionization Detector (FID) jet could become clogged with ferrule material, column bleed, or heavy molecular analytes. The clogged jet will affect...
This Information Applies To: Agilent GC Systems with Split/Splitless (S/SL) inlet
Issue
Different liners are required for different high concentration, split analysis techniques including:
General use liners
Auto inject, general use
Auto...
This Information Applies To: Agilent GC Systems with Split/Splitless (S/SL) inlet
Issue
Different liners are required for different splitless trace analysis techniques including:
General use liners
Pressure, temperature, volume (PTV)
Hot...