Hello,
We are currently running an Agilent 6460 QQQ LC/MS.
After a seemingly successful run we went to go analyze the data and found that all of our peaks had shifted considerably. We concluded that this might be due to the replacement of our inline…
Hello,
Recently, I've come across an issue where I performed a Lamp Intensity test using the Instant Pilot and it failed the 221-350nm wavelength. Since this is a relatively new lamp, I decided to look into values and that's where I saw Lab Advisor…
Hi Using Openlab 2.4 with our 6890N GC. My question is how to be able to capture a Blank Run (no injection, only FIDsignal during oven ramping) ? In the training I understood that a "Double Blank" is what I needed. But when I make a sequence, with first…
Situation: User installed Openlab C.01.05 to run an LCMS system. Was able to configure the sytem, but when they launched they would see the following error in the initializing instrument phase: MSD Error 'Installl module, 'C:\Chem32\CORE\HPMSACQ0.DLL…
Hi all Wondering if a method can cause the IP adressess to get meesed up. I tried running a new method on an agilent 5975C MS with 7890A GC integrated with Gerstel headspace and FID.. the method did run but no data was collected. and worse, I believe…
Hi, what type of analysis are you running? For example is this pesticide analysis, residual solvents, etc? I'm also curious what type of sample matrix you are using.
A drop in transmission of 219/69 and 502/69 is typically related to the source. It…
Ok. So it sounds like some progress to get the negative mode tune to complete and look ok. I would run the negative tune only. Let it complete and save the tune file. Then run a positive polarity tune immediately.
If that fails again, its probably worth…
The front inlet on my GC8890 is failing the restriction test. It passes the leak test no problem and I've done everything I can think of to fix it. I've replaced the septa, checked the gold seal, trimmed the column, baked the column, and checked the inlet…
Hello Everyone, I'm new to Open Lab CDS and I currently have version 2.2 paired with a Agilent GC-FID. I'm still learnng the software and I had a few questions in regards to calibrating and calculating uncalibrated peaks. In Open Lab CDS, how do I calculate…
This Information Applies To: Agilent GC Systems
Issue
Excessive baseline noise can be introduced at different points including sample preparation, sample introduction, separation, and the detector. The excessive background can cause reduced signal...
This Information Applies To: Agilent GC Systems
Issue
Baseline instability that is not reproducible across multiple runs can be introduced at different points including sample introduction, separation, and the detector. The baseline instability...
This Information Applies To: Agilent GC Systems
Issue
Peak fronting is present in a chromatography peak when it has an excessive asymmetry with a leading edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
This Information Applies To: Agilent GC Systems
Issue
A shift in retention time can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
A change in peak size can occur for single, multiple or all peaks.
Other chromatographic problems are identified in Basic Troubleshooting for GC Systems . Regular maintenance of your instrument...
This Information Applies To: Agilent GC Systems
Issue
Peak splitting is when a single compound is shown in the chromatogram as two peaks usually unresolved, or one of the peaks is a shoulder.
Other chromatographic problems are identified in Basic...
This Information Applies To: Agilent GC Systems
Issue
This test isolates the point of contamination to the sample introduction system, which includes the gas supply, gas supply lines, and the sample inlet. It does not include the syringe or autosampler...
This Information Applies To: Agilent GC systems
Issue
Peak tailing is present in a chromatography peak when it has an excessive asymmetry with a trailing edge. A normal peak is almost symmetrical.
Other chromatographic problems are identified...
T his Information Applies To: Agilent 8890/8860/7890/7820/6850/6890 GC Systems with TCD (Thermal Conductivity Detector)
Issue
Problems observed with thermal conductivity detector (TCD) results can have different underlying causes.
Resolution...
This Information Applies To: All GCs, 6890, 6850, 7890, 7820, 8890/8860, Intuvo 9000
Issue:
This article is a troubleshooting guide for when the Flame Ionization Detector (FID) does not ignite or the flame keeps going out.
Cause:
If the FID...