Pipeline software for untargeted lipidomics


We are used to do targeted lipidomics using LC-MS/MS. However, we want to try untargeted lipidomics. We have  an Agilent LC-QTOF, and we were wondering what is the best pipeline to do this.

We have access to Mass hunter Qual, Quant, etc but I asume this is not the best software.

We asked around and I was adviced to try Skyline, MSDial, mzMine, etc

We also see Agilent has Mass Profiler,...

The idea is to run untargeted, then do differential levels of lipids between samples. What would be the best approach? Is there databases for lipid identification integrated to these softwares?



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