QQQ error : Failed to download parameters to Instrument

The problem seems to occur during dMRM mode. When I changed the mode to MRM mode, the problem never occurred again.

The issue is that the DMRM required cycle time is greater than the cycle time set in the method. 

On the QQQ acquisition page scroll to the bottom of the page and will identify the required cycle time to perform the method. Either adjust acquisition windows or increase the cycle time, which ever has the least effect on your acquisition.