An MS related Issue.

Can someone help me with this. ?

While optimisation iam getting errors like "Peak not found during ce optimisation"

Does that mean the product ions are not stable.?

How to sole this? CE IS FROM 0-60

Fragmentation voltages from 50-250

Parents Reply
  • This message suggests that there is insufficient ion signal for Optimizer to operate properly. 

    Do you know at which point this in the optimization process that this error occurs (MS2SIM, Product Ion, MRM)? Based on this, it seems like Product ion or MRM. 

    It likely means that the product ion(s) selected is not being detected or has low abundance. I would observe the optimization process and if necessary, attempt this step manually and confirm that the product ion is suitable. 

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