Previously, the results came out like the left side, but now it comes out like the right side. Negative is normal, but there seems to be a problem in positive MS.
Please somebody help me..
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Previously, the results came out like the left side, but now it comes out like the right side. Negative is normal, but there seems to be a problem in positive MS.
Please somebody help me..
Looking at the signal axes for the positive signals. The one where you gave distinct peaks is much smaller than the other. Seems like a lot more background signal than before? Has the MS spray chamber been cleaned recently? That's where I would start. Maybe the rest of the HPLC could do with a clean/flush, in case the additional background comes from there.
What do the background mass spectra look like in both sets of data?
/Andy
Looking at the signal axes for the positive signals. The one where you gave distinct peaks is much smaller than the other. Seems like a lot more background signal than before? Has the MS spray chamber been cleaned recently? That's where I would start. Maybe the rest of the HPLC could do with a clean/flush, in case the additional background comes from there.
What do the background mass spectra look like in both sets of data?
/Andy