Is anyone had struggle with the m/z 118.1230 as a contaminant, in positive ionisation mode on a LC-QTOF?
We do lipidomic and it create a lot of problems on lipids which ionise as an [M+NH4]+ as phosphatidylinositols, cholesteryl esters and triglycerids.
Do you have any idea where it could come from? How we can reduce or eliminate the signal?
Thank you in advance!