Can I transfer an LC-MS/MS method between instruments by simply copy and pasting .m and worklist files?

Hi

If instrument configuration is same then possible otherwise may need optimisation of method after transferring..

not only the instrument configuration is the same，bu also the software version also need to be same。otherwise would be some bugs

Hi LabRat,

I would manually copy methods in to prevent any conflicts. What is the instrument?

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I have observed that when a method is transferred to a new system, you need to save it in the new system before using it. If you just copy the method and use it,  sometimes it fails. Just by saving it, it makes it work. I guess it saves some defaults from the second instrument that were missing in the method.