I have a 1200 LC system with an old single quad MS (G1956B), with an API-ES ion source. Recently I began running into an issue where the method would terminate during the run. The logbook indicates two errors: First, Spray Chamber Open (1501). Second, Spray Chamber not ready (1500). I know that it is not a software issue because I have tried using a different computer to control the instrument, and I still get the same issue. Does anyone have any helpful comments or tips on how to fix this issue?