Agilent 1290 Infinity II ELSD G7102A Communication question

Both are fine. It depends on what's available. Many modern PCs don't have a serial port any longer. A USB converter can be used, but it should be a good-quality one. At Agilent we offer a tested one. Serial communication might sound a little old-fashioned, but we're not talking about fast data rates of 240 Hz, spectra etc. Furthermore no network switch is required. So, if you do have a serial port on your PC, I would go for RS232 communication.

Both are fine. It depends on what's available. Many modern PCs don't have a serial port any longer. A USB converter can be used, but it should be a good-quality one. At Agilent we offer a tested one. Serial communication might sound a little old-fashioned, but we're not talking about fast data rates of 240 Hz, spectra etc. Furthermore no network switch is required. So, if you do have a serial port on your PC, I would go for RS232 communication.