Peak assignment algorithm in ChemStation

I am calibrating 40 peaks and while they are all baseline-resolved at mid-concentration, at higher concentrations peaks start shifting and an incorrect assasignment can occur.  Similarly, unidentified peaks close by can trigger an incorrect assignment as well.  Additionally, simply reprocessing with the same parameters can result in different assignment.  It seems that the algorithm is trying to maximize the number of assigned peaks prioritizing the number of assigned peaks over their closeness to the expected retention times.  Is my assumption correct?  How to get around it, within the constrains of the chromatographic method as it is right now?  Is there a comprehensive explanation of how this algorithm works so I can educate myself?  Thanks!

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  • no. we already have Mass Hunter module, but we are doing GC/ECD work with the chemstation that's co-loaded with  Mass Hunter.  We seem to be missing some steps(?) or some macros (?) and other details that are needed to translate the GC/ECD data to a form that's compatible for uploading to our LIMS system.  I'm saying the help files/tutorials are more geared to Mass Hunter rather than the GC analysis.   Or I'm missing something somewhere.

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