GC and Helium shortage

Hi srstrangis,

I have updated the tags for better visibility . Please see the below discussion link on using hydrogen as a carrier . I would suggest that you speak with one of our column specialist at Agilent if you are going to convert to another carrier gas type. Column size changes maybe required depending on your application. A gas change is most often, not a straight forward change.  I have also included a link to our GC calculators as there is a flow tool that will allow you to calculate column flow , head pressure etc.

Columns, Supplies, and Standards Support | Agilent

GC Calculators | Agilent

Using Hydrogen as Carrier Gas for GC and GCMS

Regards

James

James,

I was able to use the same column. I had to reduce the inlet pressure from 15 psi to 11 psi to keep the speed within the recommended range for H2.

The areas are now 5 times larger (higher sensitivity). The peaks do not resolve at baseline. I'd like to reduce the injection volume from 1 uL to 0.5 uL. The problem is that the autosampler options are 0.2 uL and 1uL. There is nothing in between. Is there any workaround with the chemstation software to inject 0.5 uL with a 10 uL syringe?

I know that one option is to use 5 uL syringes.   

James,

I was able to use the same column. I had to reduce the inlet pressure from 15 psi to 11 psi to keep the speed within the recommended range for H2.

The areas are now 5 times larger (higher sensitivity). The peaks do not resolve at baseline. I'd like to reduce the injection volume from 1 uL to 0.5 uL. The problem is that the autosampler options are 0.2 uL and 1uL. There is nothing in between. Is there any workaround with the chemstation software to inject 0.5 uL with a 10 uL syringe?

I know that one option is to use 5 uL syringes.   

Hi srstrangis,

The smaller syringe is one way. Depending on the autosampler you have , you may not be able to specify the smaller injection volume without changing syringe to 5ul. You could also stay with the injection volume, but change the method to split . The split ratio would have to be high enough to maintain a recommended total flow of 15 to 20 ml/minute on the inlet. I hope that helps. Let us know what you find.

James