Have you switched to hydrogen carrier gas? What are your experiences?

Hi everyone,

Have you switched to hydrogen from helium as your default carrier gas? What were your experiences? What preparation did you have, and what do you wish you knew?

 

I'm wondering about helium this week after C&ENews' article on NMR, which discussed helium and the problems associated with its availability.

Securing The Future Of NMR | February 15, 2016 Issue - Vol. 94 Issue 7 | Chemical & Engineering News

 

Our colleagues in NMR don't have a substitute, but in GC one can switch to hydrogen if helium availability is a problem.

 

What are your thoughts on...

  • how long did it take you to set it up and get accurate results
  • were you able to translate your methods effectively?
  • did you encounter any institutional safety problems?

 

Thanks for your insights!

- Josh

Parents
  • Here are some tips in no particular order:

    You must be careful with halogenated solvents and carbon disulfide as you may make acid in the inlet when using hydrogen carrier.  Some analyses cannot be run with hydrogen because of that.

    The optimum carrier gas linear velocity is different than helium so use the available tools to get it right.

    The signal to noise ratio on a GCMS system will be less than when running helium - up to 2x to 5x worse.

    Library matching will not be the same as when running helium.

    Hydrogen scrubs the inside of the gas regulator and supply tubing and you will see more noise for a while -- up to a few weeks -- as it does a better job cleaning than the manufacturer.

    Make sure and read the Hydrogen Safety Manual -  G3870-90101.

    The MSD pumping capacity for H2 is approximately 1/2 that of Helium.

     

    – Performance turbo: 2 mL/min

     

    – Standard turbo: 1 mL/min

     

    – Diffusion pump: 0.75 mL/min

     

    – Pressure pulsing: turbo < 3 mL/min, diffusion < 2.5 mL/min

     

Reply
  • Here are some tips in no particular order:

    You must be careful with halogenated solvents and carbon disulfide as you may make acid in the inlet when using hydrogen carrier.  Some analyses cannot be run with hydrogen because of that.

    The optimum carrier gas linear velocity is different than helium so use the available tools to get it right.

    The signal to noise ratio on a GCMS system will be less than when running helium - up to 2x to 5x worse.

    Library matching will not be the same as when running helium.

    Hydrogen scrubs the inside of the gas regulator and supply tubing and you will see more noise for a while -- up to a few weeks -- as it does a better job cleaning than the manufacturer.

    Make sure and read the Hydrogen Safety Manual -  G3870-90101.

    The MSD pumping capacity for H2 is approximately 1/2 that of Helium.

     

    – Performance turbo: 2 mL/min

     

    – Standard turbo: 1 mL/min

     

    – Diffusion pump: 0.75 mL/min

     

    – Pressure pulsing: turbo < 3 mL/min, diffusion < 2.5 mL/min

     

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