the steps in the implementation of the 850-DS Dissolution Sampling Station benefits

Hello,

It sounds like your method is not using media replacement and the cleaning was done before your testing.  If this is the case, then the refill and cleaning lines connected incorrectly should not affect your run.

Below are links to helpful resources for the 850-DS:

Agilent 850-DS Sampling Station: Cleaning Validation

As mentioned in the document above, you can contact the Dissolution Hotline by email for further recommendations.

(19) Agilent Tips and Tricks: 850-DS Dissolution Sampling Station - Videos - Dissolution - Agilent Community

The operator's manual can be found here:

(19) Operators Manuals - Wiki - Dissolution - Agilent Community

Agilent Practical Solutions Newsletter Volumne 2022 Issue 2

Agilent 850-DS Sampling Station Method Setup Quick Start Guide

Regards,

Lycrecia Caskey

First of all, thank you for your answer. I still have doubts, because the instrument was cleaned before the experiment, whether there will be such a situation: due to the wrong connection of the water outlet, the cleaning water still exists in the cleaning tank and cannot be excluded (the pipeline of the refill pump of the autosampler was connected to the cleaning pump, and the pipeline of the cleaning pump was connected to the refill pump.).
When the test is performed, the sample solution drawn by the autosampler to the injection vial is diluted.