Dear Agilent team,
do you maybe have some information on using Enhanced Matrix Removal - Lipid kit (EMR-Lipid) for lipid separation in brain homogenate (eg. prepared in ratio 1:9 in PBS). As brain homogenate has a lot of lipids and proteins, the Signal-to-Noise ratio of quantification of specific analytes using LC-MS is too low. Do you maybe think that your Enhanced Matrix Removal - Lipid kit (EMR-Lipid) could improve the sample preparation, thus lowering the matrix effect of brain homogenate? Thank you in advance.