How can we interpret the values of dissolution efficiency (DE) and mean dissolution time (MDT) in comparative dissolution studies. Thank you

Question

I am doing comparative dissolution studies of generic Valsartan, but I dont understand we will take 10% interval of dissolution efficiency or we will interpret this in another way. dissolution .

lcaskey · Accepted Answer

I am not familiar with this topic. I did an internet search and found a couple of links that may be helpful.

Below are the links I found:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824474/

and

https://www.sciencedirect.com/science/article/abs/pii/S0731708598000119

You may also find the Dissolution Discussion Group helpful.

The DDG website is www.dissolution.com

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How can we interpret the values of dissolution efficiency (DE) and mean dissolution time (MDT) in comparative dissolution studies. Thank you

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