Which column to analyze acids, amides, amines and aldehydes GC-MS

Hi Nipo,

You can find an application note from Agilent referring some of those compounds:

https://www.agilent.com/cs/library/applications/application-usp467-residual%20solvents-class1-2-3-5994-1488en-agilent.pdf

FYI, I found this note using the Scanview software from Agilent. A very useful app I would say.

community.agilent.com/.../software-supported-method-development---the-scanview-program

Thank you so much! The Scanview software from Agilent seems so useful. I didn't know it!

Hi Nipo,

If formaldehyde is involved, the best choice is an apolar column with a thick film (we do have a CP-Sil 5 CB for formaldehyde, if it is only about HCHO in water with other low boiling components, it's a 8 µm thick film). With some higher boiling components present a slightly thinner film could be beneficial. If no critical analytes are present, than any 624 column would also work and you can just check that with the appnote mentioned in the previous replies.

Regards,

Norbert