MolSieve packed column rapid analysis

Hi all,

For our analysis we are using the following MolSieve packed column:
#G3591-80074 MolSieve 5A, 80/100, 3 ft (0.91 M), 1/8 in. OD, 2 mm ID.

We need to replace this column to get twice faster analysis. For example for CH4 which has the time of retention of 4.5min at the moment, we need such column to get it on 2.3min.
In this situation, the only solution is to replace the #G3591-8007 column with one similar by the length, but with different parameters (mesh value, or to use 13X type instead of 5A, which has faster time of analysis).

Please note that changing the method parameters is not accepted, the only solution is packed column replacement with a faster analysis one.

We are thinking to replace with the following column:
#G3591-80028 MolSieve 13X, 45/60, 3 ft (0.91 M), 1/8 in. OD, 2 mm ID.
But we are not sure on it, so please advice.

Thank you in advance.

Best regards,
Alexandr

Parents
  • Hello

    To be more secure about what column is the best, I would advise you to download and use our GC Method translator. You can access for free at the link below:

    https://www.agilent.com/en/support/gas-chromatography/gccalculators

    Using this tool you can add your current method and simulate how the method would be with a new column in terms of how fast or how more efficient it would became based on the dimensions. You can't change the method a lot but at the software you can simulate any changes, as temperature ramp, carrier gas and etc if needed.

    If you change column chemistry, it's harder to predicted because elution order or time retention can change in a not proportional way in relation to the current column

    Thank you,

  • Hi Mariana,

    Thank you for your reply and recommendations.

    I've checked the GC Method translator, and it is a really useful tool, but for capillary columns only. As I am using the packed columns, there is no way to define this column in Method Translator, so to simulate the optimum parameters.

    The only solution is to find someone you have experience using different type of MolSieve packed columns with different parameters and could help me to replace my column with a suitable one to have twice faster analysis.

    Best regards,
    Alexandr 

Reply
  • Hi Mariana,

    Thank you for your reply and recommendations.

    I've checked the GC Method translator, and it is a really useful tool, but for capillary columns only. As I am using the packed columns, there is no way to define this column in Method Translator, so to simulate the optimum parameters.

    The only solution is to find someone you have experience using different type of MolSieve packed columns with different parameters and could help me to replace my column with a suitable one to have twice faster analysis.

    Best regards,
    Alexandr 

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