Best Practices for Making Good Connections

Properly fitted connections are key to optimizing separations. This post illustrates the effects of poorly fit connections and suggests resources to help. Many of us don’t spend much time thinking about...
Pass the Salt, Please – Mobile Phase Preparation for HIC

Hi again. One of the first tasks for any separation experiment is mobile phase preparation. So that’s where my colleague Sandeep is going to take the lead to describe some unique features of mobile phase...
A Tip for Preparing Robust and Consistent Mobile Phases

Consistently prepared mobile phases are key to consistent chromatography results. Order of operations can matter to more than just math. A method is only as robust as each of the components involved,...
Minimizing Metals for Best HILIC Results

In this post, learn how to successfully monitor "sticky" metabolites with a stainless steel LC. Of the analytes that you can monitor with HILIC separations, amino acids are fairly straightforward. Aside...