jli

Can I compensate for TFA ion suppression with more sample?

Discussion created by jli on Jun 5, 2020

I need 0.1% TFA to do my protein separation for now. Can I just inject more sample to make up for the loss in signal intensity on the MS side (on the scale of 10ug analyte per injection)? Will I risk damaging my QTOF in any way doing this? 

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