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Does ammonium fluoride assist ionisation? (and how?)

Question asked by peter.stockham on Jan 22, 2020

Hi I recently read a report in which 1mM ammonium fluoride was added to the LC-MS mobile phase to increase sensitivity/ionisation. Can anyone verify this is effective for ESI positive mode analysis of drugs? Can you point me to a reference that describes how this works (if it does) 

Cheers

Peter

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