has DMSO as diluent any damage effect on mass spctrometer because of sulfur content in its structure?
I think as long as you have the detector turn on after the solvent passes (solvent front) then it should be fine. Just ensure that the ion source temperature is pretty high too just to stop charring on the ion source and stop it from getting dirty quickly.
I will mark this post as assumed answered due to its age, if thats not the case, feel free to post again.
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