Last week we vented and powered off our Agilent 6650 iFunnel QTOF. When we tried to turn it on and pump down from mass hunter software (I think B 09), the rough pump ran at the beginning, but just after 10 min, then it automatically stops. After a couple of hours the The TOF Vac showed 9.94 E-01 Torr, the Quad Vac showed 8.56E-10 Torr and the rough Vac showed 741 Torr. Then we tried to pump down again, the Q-TOF panel turned to offline. I think there should be something wrong with the software and the instrument. The event log also showed “ The communication from the firmware has failed”. Any idea about what could be wrong?