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You can use Lab Advisor to monitor / set the vaccum Level for most pumps.
This can be used to debug the problem / to check if there is any vacuum generated..
If this error occours either the pump or the sensor might have failed or the pump is not able to reach the vacuum level set inside the firmware.
The vaccum pump is a membrane pump, you might be able check if the membrane welded itself to the seat due to solvent vapor or if there is any other mechanical failure.. (We don´t recommend opening the instrument)
You can get Lab Advisor here: http://labadvisor.pl29.agilent.com/latest
The screen shown above is found under "Instrument Control"
A temporary fix would be to set the vacuum level to 1000mbar (Ambient pressure) to get rid of the "not ready" state, however this essentially disables the Degassing of the solvents.