1 Reply Latest reply on Oct 24, 2018 11:22 AM by hexatriene

    Accepting (approving) outliers in Masshunter


      For environmental analysis of POP's with QQQ, we aquire at least two transitions.

      The first one to quantitate, the latter ones as qualifiers whitch should lie between ± 20% of the expected ion ratio.

      However, for very small peaks ( < 2 times LOQ) it is allowed to elevate this threshold to ± 50% and it is up to the analyst to evaluate and approve it.

      First: Is there a way to incorporate this "flexible" threshold into the quantification method software? I can only find the way to evaluate ion ratio outliers (Method tasks -> Outlier Setup tasks -> Qualifier ratio) but this is very rigid.

      Second: Is there a way for the analyst to approve an outlier in such a way that the flag is removed (or overruled) but still is registrated by the CDS?

        • Re: Accepting (approving) outliers in Masshunter

          Hi arjantaal,


          First question: No. The outlier threshold applies equally to all levels (concentrations) of qualifiers - it's not possible to give lower level concentrations larger error windows. This is something that has been requested in the past - and has been logged in our enhancement system for consideration in a future release.


          Second: There is no way for a user to override an outlier flag - however, we can register that an analyst has approved it (and which will appear on the report). However - this approval is at the sample level (meaning approved for all compounds in one sample). Once approved - this flag can be added to be displayed in a report: