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What are causes of dropping of the mass reference ions?

Question asked by ahmed1975 on Oct 6, 2017
Latest reply on Oct 9, 2017 by m4esti

Dropping of the mass reference 121m/z and 922 and no improvement even if i increased the isocratic pump flow rate from 2 mlmin to 4 ml/min. I added more Purine and HP0921 to the reference solution but no improvement. I checked the filter and it is OK. I checked if the there was air in the tube but all did not improve the abundance

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