New error in MassHunter Profinder (10.0.03): "values in ‘MFE database location’ are invalid"

Question

Hi, 
 I am trying to my usual method for Batch recursive feature extraction on LCMS-QTOF data. I am getting a new error blocking the analysis from starting. 
 "Invalid method setting. 
 One or more values in &lsquo;MFE database location&rsquo; are invalid. Please change values of &lsquo;MFE database location&rsquo; and try again." 
 As far as I can tell, my wizard settings are not asking the software to use a database. I have tried changing all sorts of the method settings with no luck. While troubleshooting I tried to rerun a previously successful analysis exactly as before but get the same error message. 
 Can any one help? 
 Many thanks

howard_sanford · Accepted Answer

Hello wplsh , 
 There are two possible causes for this error. 
 First make certain the database default.csv is present in D:\MassHunter\PCDL\ (or C:\ Masshunter\PCDL). Even though it is not used, it must be present. If it is not there or has become corrupted, download this file and put it in the PCDL folder. 
 default.zip 
 The other thing that will cause this error is setting the PC Region and Language to something other than English (US). For Profinder to work properly this must be changed back to English (US).

New error in MassHunter Profinder (10.0.03): "values in ‘MFE database location’ are invalid"

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