Can MassHunter Unknowns Pull RI data from different GC Column Types?

Hello william.mcgrath ,

There is not a way to change which RI data is being pulled from the NIST libraries in previous versions of MassHunter. The option to choose RI Type was added in current Quant 12.1, but it is currently not working and should not be used. It should be resolved in the next release of Quant but there is currently no information on when this will be available.

I'm not familiar with the NIST GC Index library, so maybe someone else will be able to chime in on that. 

If you go to Method Edit -> Advanced -> Library Search and scroll to column that says Retention Index Type you can change the column type in new version of Quant 12.1. But like Howard is saying its not working correctly. But I have figured out what its doing wrong. 

For example if you search for polar column and the NIST hit has polar column entry it will show that entry. If the NIST does not have a polar column entry but it has a semi-standard non-polar entry it will show that one. So basically if it doesn't have entry you want it will just show whatever other entry it does have. Not ideal. 

I've tried many work arounds. The only promising way I found was writing scripts to import RI into Library Editor software but even this isn't ideal because you still have to get the mass spectra into your library too. 

I am currently using version 12.0 and I don't know how to upgrade to version 12.1. Can you help me?

Hello 海光天 ,

Have your SubscribeNet administrator check to see if the download for Quant 12.1 is available for your account. If it is, for supported LCMS TQ and GCMS systems on Quant 12.0 the upgrade to 12.1 can be performed in place by running the setup for 12.1. Follow the instructions provided in the setup dialog.

If the update is not available for your account, you can reach out to your local sales and support team for upgrade options.