LCMS issues

I am working with an Agilent LC1260, MS6100 instrument and encountering the following issues:

 

  1. The vacuum system is not reaching the proper levels even after running for several hours.
  2. Recurring Configuration Issues: Each time I use the instrument, I have to reconfigure the software. How can I ensure that the configuration is retained so that this process is only required once?
  3. Connection Failure with Agilent OpenLab Acquisition: The software frequently fails to connect to the instrument. On the rare occasion that it does connect, I receive the following error message:

"Object reference not set to an instance of an object. StackTrace: at Agilent.MSDrivers.LCQuadrupole.UI.MSMethodUI.SetDeviceStatus (String xmlStatus) in z:\Rigel\MethodUI\MSMethodUI\MSMethodUI.xaml.cs:line 2618"

I am looking for solutions to these problems to streamline the operation of the instrument and software.

 

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