Working in a GMP environment and we need to transfer an LC/MS method from a site using ChemStation C.01.10 to a site using OpenLAB CDS 2.6. Most of the method settings transfer easily, but we're having some difficulties determining the appropriate threshold settings and making sure that the peak width/cycle time/dwell time are the same. The method is quantitative so these are quite impactful.
In the original ChemStation method the threshold is set at 50, but it looks like that option isn't available in OpenLAB 2.6? Does anyone know how Openlab treats the data instead?
We'd also assumed that the time filter window in OpenLab was the same as the combination of the time filter and the peak width in ChemStation, but we seem to be getting a different cycle time (0.479s rather than 1.9s). Is the scan/dwell time a new option in Openlab and is this what needs to be edited to get the same cycle time?
Finally, I'm assuming that "Profile" data storage in Openlab is equivalent to "Full" data stroage in CS?
Thanks in advance! Chris