The compressibility compensation default setting is 100 × 10-6 /bar for the
pump. This setting represents an average value. Under normal conditions the
default setting reduces the pressure pulsation to values (below 1% of system
pressure) that will be sufficient for most applications and for all gradient
analyses. For applications using sensitive detectors, the compressibility
settings can be optimized by using the values for the various solvents
described in Table 9 on page 61. If the solvent in use is not listed in the
compressibility tables, when using isocratic mixtures of solvents and if the
default settings are not sufficient for your application the following procedure
can be used to optimize the compressibility settings.
