SIM quant on 7010QQQ different results than SIM on 5977 GCMS

Running same calibration set on a 5977 GCMS and a 7010QQQ both in SIM mode. 7010 is run split 1:25 and several different gain values on 7010 while 5977 is splitless with uniform gain. I get vastly different results when running sample calibration and sample set on both instruments. Why?

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