In my lab, we set a method for the analysis of 10 pesticides with an single quadrupole GC/MS in SIM mode. No problems. Now we want to add, analyse and quantify more than 100 compounds in SIM too but the MS methos alerts me that 420 ions are too much (130 compounds x 3 ions = 420 ions). So, my question is: How can I analyse and, most important thing, quantify all these new compounds?
Thank you so much!