Ion 44 baseline

hello ebosinceanu,

1) to see when/how the unwanted peaks come:

               please create an extracted TIC once: Chromatogram > Extract ion chromatogram > type in all masses (18, 28...)

EXAMPLE:

now we can see if it is a unique entry or if it changes during the run.

2) how is the inlet EPC set:

      ~ which inlet? (S/SL, MMi...)

      ~ which mode? (S, splitless...)

      ~ which total flow? or is GasSaver on?

      ~Background:

        Some inlets, although leak free, tend to increase N2 values if the total flow during the run is very low.

           Simulation: manual tune > SCAN.

             Now set the total as it is in run mode,

               if nothing is found: increase the temperature of the GC

3) For leak search @MSD a spray is mandatory:

      (aero duster spray or) electronic freeze spray down to -45°C (inside ACQ: manual scan: profile on mass 83)

      Then ferrules are not stressed too much, because many users have already destroyed the MS transferline by preventive "over" tightening.

         typical spray (hopefully this will not be seen as advertising here ;-) ) 

regards, M

hello ebosinceanu,

1) to see when/how the unwanted peaks come:

               please create an extracted TIC once: Chromatogram > Extract ion chromatogram > type in all masses (18, 28...)

EXAMPLE:

now we can see if it is a unique entry or if it changes during the run.

2) how is the inlet EPC set:

      ~ which inlet? (S/SL, MMi...)

      ~ which mode? (S, splitless...)

      ~ which total flow? or is GasSaver on?

      ~Background:

        Some inlets, although leak free, tend to increase N2 values if the total flow during the run is very low.

           Simulation: manual tune > SCAN.

             Now set the total as it is in run mode,

               if nothing is found: increase the temperature of the GC

3) For leak search @MSD a spray is mandatory:

      (aero duster spray or) electronic freeze spray down to -45°C (inside ACQ: manual scan: profile on mass 83)

      Then ferrules are not stressed too much, because many users have already destroyed the MS transferline by preventive "over" tightening.

         typical spray (hopefully this will not be seen as advertising here ;-) ) 

regards, M