• State Not Answered
  • Replies 2 replies
  • Subscribers 62 subscribers
  • Views 669 views
  • Users 0 members are here
Related

Agilent Knowledge Portal

Find maintenance, best practice, and troubleshooting articles.

Agilent Knowledge Portal

the detection limit is 0.6ppb for Zinc when we rinsed our Digi Tube with HNO3, what should I do to reduce the detection limit?

Kitty2022

Hi 

we still got very high Detection limit of 0.6 ppb for Zinc after we rinsed the Digi Tube with 2% HNO3. Does anybody know how to reduce the detection limit? 

we use 2% HNO3 to rinse the Digi Tube, then fill the tube with 2% HNO3, and let them stand overnight with a lid covering. next day , we created the following calibration curve, but still have high background which lead to 0.6ppb. 

we assume there are possibly two reasons to introduce this high background: 

1. water quality. we use water for injection from Baxter. please see the below picture. we want to know what the background reading if milli Q water is used. 

2. another is the instrument setting. we set the instrument setting: 

Thank you 

Best regards, 

Di Xu

Parents
  • 0

    I never use sterile water for ICP-MS since it's not good for trace metal work (that wasn't its designed purpose). Sterile water is typically just distilled water. You will want DI, Milli-Q (18.2 megaohm) or comparable.

    In a lab with good reagents (water and optima grade acids), good lab practice (prewashing), on a clean instrument (clean sample intro) my zinc counts are <1000. This is not always achievable in labs if proper care is not taken during sample prep or if the lab environment is not clean enough. 

  • 0 in reply to Chelsea Tajc

    Hi Cheltajc, 

    Thank you for your suggestions. 

    yes, I agreed with you . yesterday we tried different water and found out that the water we are currently using has around 11 ppb zinc. 

    after we changed the water, we obtain the following results: 

    now the root cause was found. 

    Thank  you

    Best regards, 

    Di Xu

Reply Children
No Data
Was this helpful?
Privacy Statement
Terms of Use
Contact Us
Site Help